Structural Studies of the Interaction between mGlu5 and Allosteric Modulators
The metabotropic glutamate receptor subtype 5 (mGlu5), a class C G-protein coupled receptor (GPCR), is involved in cognitive function through diverse signaling pathways that modulate synaptic plasticity. Modulators of mGlu5 hold exciting potential for the development of novel treatment strategies th...
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Format: | Others |
Language: | en |
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VANDERBILT
2013
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Online Access: | http://etd.library.vanderbilt.edu/available/etd-07172013-164828/ |