THE TRAFFICKING OF AMPHIREGULIN IN POLARIZED EPITHELIAL CELLS
Epithelial cells establish apical and basolateral (BL) membranes with distinct protein and lipid compositions. To achieve this spatial asymmetry, the cell utilizes a variety of mechanisms for differential sorting, delivery and retention of cell surface proteins. The EGF receptor (EGFR) and its ligan...
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Language: | en |
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VANDERBILT
2011
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Online Access: | http://etd.library.vanderbilt.edu/available/etd-07112011-131421/ |