THE TRAFFICKING OF AMPHIREGULIN IN POLARIZED EPITHELIAL CELLS

Epithelial cells establish apical and basolateral (BL) membranes with distinct protein and lipid compositions. To achieve this spatial asymmetry, the cell utilizes a variety of mechanisms for differential sorting, delivery and retention of cell surface proteins. The EGF receptor (EGFR) and its ligan...

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Bibliographic Details
Main Author: Gephart, Jonathan David
Other Authors: Steve Hanks
Format: Others
Language:en
Published: VANDERBILT 2011
Subjects:
Online Access:http://etd.library.vanderbilt.edu/available/etd-07112011-131421/