Differential contributions of host-derived matrix metalloproteinases in mammary tumor growth in the bone microenvironment

Breast to bone metastasis is a common event during breast cancer progression. The resultant lesions often cause extensive bone destruction that results in a number of complications including intense pain that dramatically affects the patients quality of life and leads to increased morbidity. Underst...

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Bibliographic Details
Main Author: Thiolloy, Sophie
Other Authors: Lynn Matrisian
Format: Others
Language:en
Published: VANDERBILT 2009
Subjects:
Online Access:http://etd.library.vanderbilt.edu/available/etd-07012009-161714/