The focal adhesion localization of p130Cas: dynamics, targeting mechanism, and signaling.

Focal adhesions (FAs) are sites at the interface between the cell and the ECM, linking integrin receptors and the actin cytoskeleton. In addition to serving as a structural platform, these sites are also robust sites of tyrosine phosphorylation and integrin signaling. When cells become adherent to t...

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Bibliographic Details
Main Author: Donato, Dominique Maria
Other Authors: Roy Zent, MD, Ph.D.
Format: Others
Language:en
Published: VANDERBILT 2010
Subjects:
Online Access:http://etd.library.vanderbilt.edu/available/etd-06302010-180728/