Accumulation of γKetoaldehyde-modified Protein in Normal and Fibrotic Lung
γKetoaldehydes are generated by free radical peroxidation and cyclooxygenation of phospholipid-esterified arachidonic acid. γKetoaldehydes covalently bind to protein lysine residues and is emerging as a mechanistic link between pathogenic reactive oxygen species and disease progression. However, t...
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Language: | en |
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VANDERBILT
2016
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Online Access: | http://etd.library.vanderbilt.edu/available/etd-06272016-141540/ |