Accumulation of γKetoaldehyde-modified Protein in Normal and Fibrotic Lung

γKetoaldehydes are generated by free radical peroxidation and cyclooxygenation of phospholipid-esterified arachidonic acid. γKetoaldehydes covalently bind to protein lysine residues and is emerging as a mechanistic link between pathogenic reactive oxygen species and disease progression. However, t...

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Bibliographic Details
Main Author: Mont, Stacey
Other Authors: Michael Freeman
Format: Others
Language:en
Published: VANDERBILT 2016
Subjects:
Online Access:http://etd.library.vanderbilt.edu/available/etd-06272016-141540/