A Biochemical Characterization of the DNA Glycosylase DEMETER
The methylation state of DNA is important for gene expression, gene imprinting, X-chromosome inactivation, and transposon silencing in mammals and plants. DNA methylation is established by methyltransferases to mark a silenced gene in the form of 5-methylcytosine (5mC). The mechanism of 5mC removal...
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Language: | en |
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VANDERBILT
2014
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Online Access: | http://etd.library.vanderbilt.edu/available/etd-06252014-123405/ |