A Biochemical Characterization of the DNA Glycosylase DEMETER

The methylation state of DNA is important for gene expression, gene imprinting, X-chromosome inactivation, and transposon silencing in mammals and plants. DNA methylation is established by methyltransferases to mark a silenced gene in the form of 5-methylcytosine (5mC). The mechanism of 5mC removal...

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Bibliographic Details
Main Author: Brooks, Sonja Claudia
Other Authors: Walter Chazin
Format: Others
Language:en
Published: VANDERBILT 2014
Subjects:
Online Access:http://etd.library.vanderbilt.edu/available/etd-06252014-123405/