Tie1 Attenuation Reduces Atherosclerosis in a Dose Dependent and Shear Stress Specific Manner
Although it is known that the response of endothelial cells to atherogenic disturbed flow is distinct from that elicited by non-atherogenic laminar flow, the mechanisms involved are poorly understood. Observing that expression of the endothelial receptor tyrosine kinase, Tie1, is evident only at reg...
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| Format: | Others |
| Language: | en |
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VANDERBILT
2010
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| Online Access: | http://etd.library.vanderbilt.edu//available/etd-06182010-135732/ |