OVEREXPRESSION OF ADENYLATION DOMAINS FOR THE IDENTIFICATION OF THE BIOSYNTHETIC PATHWAY OF K-26, AN ACE INHIBITING METABOLITE
K-26 is an acidic tripeptide molecule with ACE inhibitory activity. It represents one of three distinct classes of unique phosphonate containing compounds found in nature. Previous work has found that unlike other C-P bond containing compounds, its biosynthetic pathway does not contain the C-P bond...
Main Author: | |
---|---|
Other Authors: | |
Format: | Others |
Language: | en |
Published: |
VANDERBILT
2009
|
Subjects: | |
Online Access: | http://etd.library.vanderbilt.edu//available/etd-04062009-180343/ |