IDENTIFICATION OF PROTEIN MARKERS OF DRUG-INDUCED NEPHROTOXICITY BY MALDI MS: IN VIVO DISCOVERY OF UBIQUITIN-T

This study demonstrated the utility of direct tissue MALDI MS in identifying early markers of antibiotic induced nephrotoxicity. Using a histology directed approach, twelve proteins were identified as having statistically significant changes as a result of gentamicin and kanamycin treatment. These p...

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Bibliographic Details
Main Author: Herring, Kristen
Other Authors: Richard Caprioli
Format: Others
Language:en
Published: VANDERBILT 2009
Subjects:
Online Access:http://etd.library.vanderbilt.edu//available/etd-04022009-103327/