IDENTIFICATION OF PROTEIN MARKERS OF DRUG-INDUCED NEPHROTOXICITY BY MALDI MS: IN VIVO DISCOVERY OF UBIQUITIN-T
This study demonstrated the utility of direct tissue MALDI MS in identifying early markers of antibiotic induced nephrotoxicity. Using a histology directed approach, twelve proteins were identified as having statistically significant changes as a result of gentamicin and kanamycin treatment. These p...
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Format: | Others |
Language: | en |
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VANDERBILT
2009
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Online Access: | http://etd.library.vanderbilt.edu//available/etd-04022009-103327/ |