Loss of p120ctn : its effect on cadherin levels, development, and tumor progression
p120 binds and is thought to regulate the cell-cell adhesion molecule E-cadherin. Experiments in a p120-deficient carcinoma cell line suggest a critical role for p120 in stabilizing E-cadherin. p120 downregulation occurs in a wide range of cancers and frequently correlates with E-cadherin loss. Thus...
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| Format: | Others |
| Language: | en |
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VANDERBILT
2005
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| Online Access: | http://etd.library.vanderbilt.edu/available/etd-04012005-151452/ |