Effects of natural products on the activity of human topoisomerase II
Topoisomerase II plays many essential roles in genome maintenance. To carry out its physiological functions, the enzyme generates transient double-stranded breaks in the DNA to help resolve topological problems that occur naturally. Thus, while essential to cell survival, topoisomerase II has the p...
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| Format: | Others |
| Language: | en |
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VANDERBILT
2016
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| Online Access: | http://etd.library.vanderbilt.edu/available/etd-03282016-032802/ |