Determining the Mechanism of SV40-induced DNA Damage

The ability of SV40 to activate the DNA damage response raises the question of whether the virus also induces DNA damage. Broken nuclear DNA in SV40-infected BSC40 cells could be detected at 5 hours post infection (hpi) using Comet and TUNEL assays. DNA breaks were not detected during infections of...

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Bibliographic Details
Main Author: Dulaney, Weston Patrick
Other Authors: Ellen Fanning
Format: Others
Language:en
Published: VANDERBILT 2011
Subjects:
Online Access:http://etd.library.vanderbilt.edu/available/etd-03282011-101620/