Determining the Mechanism of SV40-induced DNA Damage
The ability of SV40 to activate the DNA damage response raises the question of whether the virus also induces DNA damage. Broken nuclear DNA in SV40-infected BSC40 cells could be detected at 5 hours post infection (hpi) using Comet and TUNEL assays. DNA breaks were not detected during infections of...
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Language: | en |
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VANDERBILT
2011
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Online Access: | http://etd.library.vanderbilt.edu/available/etd-03282011-101620/ |