Enrichment of AU-rich Element Containing mRNAs during Intestinal Cell Epithelial-mesenchymal Transition: Roles, Mechanisms, and Significance
Colon cancer progression is frequently characterized by activating mutations in Ras and emergence of the tumor promoting effects of TGF-beta signaling. Ras-inducible rat intestinal epithelial cells (RIE:iRas) undergo a well described epithelial to mesenchymal transition (EMT), acquiring an invasive...
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Language: | en |
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VANDERBILT
2008
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Online Access: | http://etd.library.vanderbilt.edu/available/etd-03272008-140527/ |