Identification of a role for integrin alpha 5 in colonic epithelial morphogenesis

Apico-basolateral polarity is a fundamental property of epithelial cells, and its loss is a hallmark of colorectal cancer (CRC). Role(s) for lateral integrins in this polarization process and the consequences of their disruption are incompletely understood. We observed an increase in collagen disorg...

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Bibliographic Details
Main Author: Starchenko, Alina
Other Authors: Matthew Tyska
Format: Others
Language:en
Published: VANDERBILT 2017
Subjects:
Online Access:http://etd.library.vanderbilt.edu/available/etd-03202017-164819/