PURIFICATION, CHARACTERIZATION AND RECONSTITUTION OF DRS2 PROTEIN, A PHOSPHOLIPID FLIPPASE FROM BUDDING YEAST

Type-IV P-type ATPases are putative phospholipid flippases that translocate specific phospholipid substrates from the exofacial to the cytosolic leaflet of membranes to generate phospholipid asymmetry. However, flippase activity has not been reconstituted with any purified type-IV P-type ATPase, and...

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Bibliographic Details
Main Author: Zhou, Xiaoming
Other Authors: Todd R. Graham
Format: Others
Language:en
Published: VANDERBILT 2010
Subjects:
Online Access:http://etd.library.vanderbilt.edu/available/etd-03192010-142021/