Examination of Candidate Exonic Variants that Confer Susceptibility to Alzheimer Disease in the Amish

Alzheimer disease (AD) is the most common cause of dementia. As with many complex diseases, the identified variants do not explain the total expected genetic risk that is based on heritability estimates for AD. Isolated founder populations, such as the Amish, are advantageous for genetic studies as...

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Bibliographic Details
Main Author: D'Aoust, Laura Nicole
Other Authors: Paul Newhouse
Format: Others
Language:en
Published: VANDERBILT 2015
Subjects:
Online Access:http://etd.library.vanderbilt.edu/available/etd-03182015-094142/