Mechanism of Quinolone Action and Resistance in Bacterial and Human Type II Topoisomerases
<p>Quinolones are the most commonly prescribed antibacterials worldwide; however, their clinical utility is threatened by the rising occurrence of resistance. Quinolones kill bacterial cells by increasing the level of DNA breaks generated by the type II topoisomerases gyrase and topoisomerase...
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| Format: | Others |
| Language: | en |
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VANDERBILT
2014
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| Online Access: | http://etd.library.vanderbilt.edu/available/etd-03072014-142354/ |