Structural and functional determinants of effective CD8+ T cell suppression of HIV-1 replication
CD8+ T cells are a critical component of an HIV-specific immune response. Our studies aimed to define the T cell receptor (TCR) structural determinants as well as effector functions associated with CD8+ T cell suppression of HIV replication. We demonstrate biased gene usage in dominant HIV epitope-s...
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| Format: | Others |
| Language: | en |
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VANDERBILT
2009
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| Online Access: | http://etd.library.vanderbilt.edu//available/etd-03022009-225040/ |