Structural Studies of Inhibition of the Human Inducible Prostaglandin E Synthase MPGES1
The inducible enzyme microsomal prostaglandin E synthase 1 (MPGES1) is a glutathione-dependent prostaglandin H2 isomerase that has been implicated in a variety of inflammatory diseases and several forms of cancer. While there are currently no available drugs that selectively inhibit its activity, M...
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| Format: | Others |
| Language: | en |
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VANDERBILT
2012
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| Online Access: | http://etd.library.vanderbilt.edu/available/etd-02202012-105424/ |