Molecular Bases of the Reduced Osteogenic Differentiation Potential in Nf1 Deficient Osteoprogenitors

Neurofibromatosis type 1 results from mutations in NF1, a gene that encodes Neurofibromin. This common genetic condition is associated with tibial pseudarthrosis (PA), whose etiology is unknown but thought to involve defective bone-repairing osteoprogenitors. The main objective of my thesis was to d...

Full description

Bibliographic Details
Main Author: Tahaei, Seyedmohammad Ebrahim
Other Authors: Florent Elefteriou
Format: Others
Language:en
Published: VANDERBILT 2018
Subjects:
Online Access:http://etd.library.vanderbilt.edu/available/etd-01222018-164000/