Airway Bacteria Drive a Progressive COPD-Like Phenotype in Mice with Polymeric Immunoglobulin Receptor Deficiency
Mechanisms driving persistent airway inflammation in chronic obstructive pulmonary disease (COPD) are incompletely understood. As secretory immunoglobulin A (SIgA) deficiency in small airways has been reported in COPD patients, we hypothesized that immunobarrier dysfunction resulting from reduced SI...
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| Format: | Others |
| Language: | en |
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VANDERBILT
2017
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| Online Access: | http://etd.library.vanderbilt.edu/available/etd-01192017-144749/ |