A study of small heat shock proteins structure and function by cryo-electron microscopy.
Small heat shock proteins (sHSPs) are a ubiquitous family of chaperones that protect unfolded proteins from irreversible aggregation in the cell. Human sHSPs are associated with the pathology of a variety of diseases. The high resolution structures of mammalian members of the sHSP family have not ye...
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Language: | en |
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VANDERBILT
2008
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Online Access: | http://etd.library.vanderbilt.edu//available/etd-01162008-104354/ |