THE ROLE OF ACTIVATING MUTATIONS IN THE FERM DOMAIN OF JANUS KINASE 3 IN THE DEVELOPMENT OF ADULT T-CELL LEUKEMIA/LYMPHOMA
Adult T-cell leukemia/lymphoma (ATLL) is an incurable peripheral T-cell malignancy where most patients succumb within the first year of diagnosis. Development of ATLL requires human T-cell lymphotrophic virus type 1 (HTLV-I) retroviral infection followed by accumulation of somatic mutations and chan...
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| Format: | Others |
| Language: | en |
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VANDERBILT
2013
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| Online Access: | http://etd.library.vanderbilt.edu/available/etd-01072013-121936/ |