Targeting breast cancer with natural forms of vitamin E and simvastatin

Targeting breast cancer with natural forms of vitamin E and simvastatin

Breast cancer is the second leading cause of death due to cancer in women. A number of effective therapeutic strategies have been implemented in clinics to cope with the disease yet recurrent disease and toxicity reduce their effectiveness. Hence, there is a need to identify and develop more effecti...

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Bibliographic Details
Main Author: Gopalan, Archana
Format: Others
Language:English
Published: 2012
Subjects:
Breast cancer
Vitamin E
Simvastatin
Apoptosis
Stem cells
TIC
Mevalonate pathway
Ceramide synthesis pathways
Death receptor 5 (DR5)
c-Jun N-terminal kinase/C/EBP homologous protein (JNK/CHOP)
FLICE inhibitory protein (c-FLIP)
B-cell lymphoma 2 (Bcl-2)
Survivin
Signal transducer and activator of transcription 3 (Stat3)
Bcl-xL
Cyclin D1
c-Myc
Online Access:http://hdl.handle.net/2152/ETD-UT-2012-05-5520

Internet

http://hdl.handle.net/2152/ETD-UT-2012-05-5520

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