Spliceosome assembly and rearrangements : understanding how snRNPs are built and helicases function

Pre-mRNA splicing by the spliceosome requires the precise and regulated efforts of the five snRNAs (U1, U2, U4, U5, and U6) and numerous associated proteins. Following assembly and activation of the spliceosome, two consecutive reactions result in intron removal and exon ligation from pre-mRNA subst...

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Bibliographic Details
Main Author: Lardelli, Rea Martine
Format: Others
Language:English
Published: 2011
Subjects:
Online Access:http://hdl.handle.net/2152/ETD-UT-2010-08-1608