The relationship between glycine receptor agonist efficacy and allosteric modulation

The glycine receptor (GlyR) is a ligand-gated ion channel member of the cys-loop receptor superfamily, responsible for inhibitory neurotransmission in the brain and spinal cord. Both glycine and the partial agonist taurine act as endogenous ligands of the GlyR. Taurine-activated GlyR may have a role...

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Bibliographic Details
Main Author: Kirson, Dean
Format: Others
Language:en
Published: 2014
Subjects:
Online Access:http://hdl.handle.net/2152/24808