The relationship between glycine receptor agonist efficacy and allosteric modulation
The glycine receptor (GlyR) is a ligand-gated ion channel member of the cys-loop receptor superfamily, responsible for inhibitory neurotransmission in the brain and spinal cord. Both glycine and the partial agonist taurine act as endogenous ligands of the GlyR. Taurine-activated GlyR may have a role...
Main Author: | |
---|---|
Format: | Others |
Language: | en |
Published: |
2014
|
Subjects: | |
Online Access: | http://hdl.handle.net/2152/24808 |