Mechanism of phospholipid induction of cell migration

Lysophosphatidic acid (LPA) is a potent bioactive lipid component of oxidized low density lipoproteins (oxLDL). High concentrations of LPA have been detected in human atherosclerotic plaques. Our data has shown that LPA highly induces smooth muscle cell (SMC) migration. Cyr61, a matricellular protei...

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Bibliographic Details
Main Author: Wu, Dongwei
Format: Others
Published: Trace: Tennessee Research and Creative Exchange 2011
Subjects:
Online Access:http://trace.tennessee.edu/utk_graddiss/1040