NOVEL CONSTITUTIVELY ACTIVE POINT MUTATIONS IN THE NH2 DOMAIN OF CXCR2 CAPTURE THE RECEPTOR IN DIFFERENT ACTIVATION STATES
Chemokines are structurally and functionally related 8-10 kDa proteins defined by four conserved cysteine residues. They consist of a superfamily of proinflammatory mediators that promote the recruitment of various kinds of leukocytes and other cell types through binding to their respective chemokin...
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| Format: | Others |
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Trace: Tennessee Research and Creative Exchange
2010
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| Online Access: | http://trace.tennessee.edu/utk_graddiss/901 |