Analysis of polymorphism in human cytomegalovirus (HCMV) chemokine, vCXCL-1, and its role in cellular activation

The human cytomegalovirus (HCMV) viral chemokine gene, UL146, shows a high degree of variability in clinical isolates. The UL146-produced viral chemokine, vCXCL-1, has homology to CXC chemokines and is predicted to be an immune modulator that may contribute to the pathogenesis of HCMV infections....

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Bibliographic Details
Main Author: Heo, Jinho
Format: Others
Published: Trace: Tennessee Research and Creative Exchange 2010
Subjects:
Online Access:http://trace.tennessee.edu/utk_graddiss/885