DNA-Protein Cross-Linking by Pyrrolizidine Alkaloids
Pyrrolizidine alkaloids (PAs) are natural plant compounds found in hundreds of plant species worldwide and are reported to have cytotoxic, carcinogenic, antimitotic, and gentotoxic activity. PAs are metabolized by the cytochrome P450 (CYP) sytem to the pyrrole or the N-oxide form. They pyrroles are...
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DigitalCommons@USU
1997
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Online Access: | https://digitalcommons.usu.edu/etd/3919 https://digitalcommons.usu.edu/cgi/viewcontent.cgi?article=4926&context=etd |