Analyzing the effects of Ca<sup>2+</sup> dynamics on mitochondrial function in health and disease

Mitochondria plays a crucial role in cells by maintaining energy metabolism and directing cell death mechanisms by buffering calcium (Ca2+ )from cytosol. Therefore, the Ca2+ overload of mitochondria due to the upregulated cytosolic Ca2+ , observed in many neurological disorders is hypothesized to be...

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Bibliographic Details
Main Author: Toglia, Patrick
Format: Others
Published: Scholar Commons 2018
Subjects:
Online Access:https://scholarcommons.usf.edu/etd/7652
https://scholarcommons.usf.edu/cgi/viewcontent.cgi?article=8849&amp;context=etd