Mechanism Elucidation and Inhibitor Discovery against Serine and Metallo-Beta-Lactamases Involved in Bacterial Antibiotic Resistance

The emergence and proliferation of Gram-negative bacteria expressing β-lactamases is a significant threat to human health. β-Lactamases are enzymes that degrade the β-lactam antibiotics (e.g., penicillins, cephalosporins, monobactams, and carbapenems) that we use to treat a diverse range of...

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Bibliographic Details
Main Author: Pemberton, Orville A.
Format: Others
Published: Scholar Commons 2017
Subjects:
Online Access:https://scholarcommons.usf.edu/etd/7435
https://scholarcommons.usf.edu/cgi/viewcontent.cgi?article=8632&context=etd