The Role of Sgs1 and Exo1 in the Maintenance of Genome Stability.
Genome instability is a hallmark of human cancers. Patients with Bloom’s syndrome, a rare chromosome breakage syndrome caused by inactivation of the RecQ helicase BLM, result in phenotypes associated with accelerated aging and develop cancer at a very young age. Patients with Bloom’s syndrom...
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| Format: | Others |
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Scholar Commons
2017
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| Online Access: | http://scholarcommons.usf.edu/etd/7006 http://scholarcommons.usf.edu/cgi/viewcontent.cgi?article=8203&context=etd |