Significance of PTEN Phosphorylation and its Nuclear Function in Lung Cancer

Phosphorylation mediated inactivation of PTEN leads to multiple malignancies with increased severity. However, the consequence of such inactivation on downstream functions of PTEN are poorly understood. Therefore, the objective of my thesis is to ascertain the molecular mechanisms by which PTEN phos...

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Bibliographic Details
Main Author: Malaney, Prerna
Format: Others
Published: Scholar Commons 2016
Subjects:
Online Access:http://scholarcommons.usf.edu/etd/6539
http://scholarcommons.usf.edu/cgi/viewcontent.cgi?article=7736&context=etd