Targeting T-bet for Prevention of Graft-Versus-Host Disease and Leukemia Relapse after Allogeneic Hematopoietic Stem Cell Transplantation

Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is an effective therapeutic option for many malignant diseases. However, the efficacy of allo-HSCT is limited by the occurrence of destructive graft-versus-host disease (GVHD). Since allogeneic T cells are the driving force in the develo...

Full description

Bibliographic Details
Main Author: Fu, Jianing
Format: Others
Published: Scholar Commons 2015
Subjects:
Online Access:http://scholarcommons.usf.edu/etd/5828
http://scholarcommons.usf.edu/cgi/viewcontent.cgi?article=7024&context=etd