Regulation and Targeting of the FANCD2 Activation in DNA Repair
Fanconi anemia (FA) is a genome instability syndrome that is clinically manifested by bone marrow failure, congenital defects, and elevated cancer susceptibility. The FA pathway is known to regulate the repair of DNA interstrand crosslinks in part through DNA homologous recombination (HR) repair. Up...
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Scholar Commons
2015
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Online Access: | http://scholarcommons.usf.edu/etd/5652 http://scholarcommons.usf.edu/cgi/viewcontent.cgi?article=6850&context=etd |