Regulation and Targeting of the FANCD2 Activation in DNA Repair

Fanconi anemia (FA) is a genome instability syndrome that is clinically manifested by bone marrow failure, congenital defects, and elevated cancer susceptibility. The FA pathway is known to regulate the repair of DNA interstrand crosslinks in part through DNA homologous recombination (HR) repair. Up...

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Bibliographic Details
Main Author: Caceres, Valentina Celeste
Format: Others
Published: Scholar Commons 2015
Subjects:
Online Access:http://scholarcommons.usf.edu/etd/5652
http://scholarcommons.usf.edu/cgi/viewcontent.cgi?article=6850&context=etd