Potential Targeted Therapeutic Strategies for Overcoming Resistance in BRAF Wild Type Melanoma

Melanoma manifests itself from the malignant transformation of melanocytes and represents the deadliest form of skin cancer, being responsible for the disproportionate majority of all skin cancer deaths. The 2002 discovery that 50% of all melanoma patients possess activating BRAF mutations ignited a...

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Bibliographic Details
Main Author: Rebecca, Vito William
Format: Others
Published: Scholar Commons 2014
Subjects:
AKT
MEK
RTK
Online Access:http://scholarcommons.usf.edu/etd/5112
http://scholarcommons.usf.edu/cgi/viewcontent.cgi?article=6308&context=etd