Synthesis and Evaluation of 3-Aryl-4(1H)-Quinolones as Orally Active Antimalarials: Overcoming Challenges in Solubility, Metabolism, and Bioavailability
Infectious diseases are the second leading cause of deaths in the world with malaria being responsible for approximately the same amount of deaths as cancer in 2012. Despite the success in malaria prevention and control measures decreasing the disease mortality rate by 45% since 2000, the developmen...
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| Format: | Others |
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Scholar Commons
2014
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| Online Access: | https://scholarcommons.usf.edu/etd/5080 https://scholarcommons.usf.edu/cgi/viewcontent.cgi?article=6276&context=etd |