The Assessment of an In-vitro Model for Evaluating the Role of PARP in Ethanol-mediated Hepatotoxicity

The Assessment of an In-vitro Model for Evaluating the Role of PARP in Ethanol-mediated Hepatotoxicity

This investigation assesses the role of poly(ADP-ribose) polymerase in ethanol-mediated hepatotoxicity using the untransfected HepG2 hepatocellular carcinoma line, an established, well-characterized toxicological model. HepG2 cells were treated with ethanol at concentrations between 100 mM and 800 m...

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Bibliographic Details
Main Author:	Coyle, Jayme
Format:	Others
Published:	Scholar Commons 2013
Subjects:	Cytotoxicity Ethanol Insensitivity HepG2 Poly(ADP-Ribsoe) Polymerase Toxicology
Online Access:	http://scholarcommons.usf.edu/etd/4810 http://scholarcommons.usf.edu/cgi/viewcontent.cgi?article=6006&context=etd

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