The Assessment of an In-vitro Model for Evaluating the Role of PARP in Ethanol-mediated Hepatotoxicity

This investigation assesses the role of poly(ADP-ribose) polymerase in ethanol-mediated hepatotoxicity using the untransfected HepG2 hepatocellular carcinoma line, an established, well-characterized toxicological model. HepG2 cells were treated with ethanol at concentrations between 100 mM and 800 m...

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Bibliographic Details
Main Author: Coyle, Jayme
Format: Others
Published: Scholar Commons 2013
Subjects:
Online Access:http://scholarcommons.usf.edu/etd/4810
http://scholarcommons.usf.edu/cgi/viewcontent.cgi?article=6006&context=etd