Development and Optimization of Kinetic Target-Guided Synthesis Approaches Targeting Protein-Protein Interactions of the Bcl-2 Family
Kinetic target-guided synthesis (TGS) and in situ click chemistry are among unconventional discovery strategies having the potential to streamline the development of protein-protein interaction modulators (PPIMs). In kinetic TGS and in situ click chemistry, the target is directly involved in the ass...
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| Format: | Others |
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Scholar Commons
2012
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| Online Access: | http://scholarcommons.usf.edu/etd/4351 http://scholarcommons.usf.edu/cgi/viewcontent.cgi?article=5547&context=etd |