Statistical Estimation of Physiologically-based Pharmacokinetic Models: Identifiability, Variation, and Uncertainty with an Illustration of Chronic Exposure to Dioxin and Dioxin-like-compounds.

Assessment of human exposure to environmental chemicals is inherently subject to uncertainty and variability. There are data gaps concerning the inventory, source, duration, and intensity of exposure as well as knowledge gaps regarding pharmacokinetics in general. These gaps result in uncertainties...

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Bibliographic Details
Main Author: Thompson, Zachary John
Format: Others
Published: Scholar Commons 2012
Subjects:
Online Access:http://scholarcommons.usf.edu/etd/4241
http://scholarcommons.usf.edu/cgi/viewcontent.cgi?article=5437&context=etd