Design and Synthesis of Protein-Protein Interaction Inhibitor Scaffolds

Many currently relevant diseases such as cancer arise from altered biological pathways that rely on protein-protein interactions. The proteins involved in these interactions contain certain functional domains that are responsible for the protein's biological activities. These domains consist...

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Bibliographic Details
Main Author: Badger, David B.
Format: Others
Published: Scholar Commons 2012
Subjects:
NMR
p53
Online Access:http://scholarcommons.usf.edu/etd/3964
http://scholarcommons.usf.edu/cgi/viewcontent.cgi?article=5160&context=etd