A new approach to kainoids: Total syntheses of (-)-kainic acid and (+)-allokainic acid

(-)-Kainic acid and its C-4 epimer, (+)-allokainic acid are parent members of a class of substituted pyrrolidines known as kainoids. They have been found to exhibit powerful biological properties, principally neuroexcitatory. Kainic acid has become especially important in the study of Alzheimer'...

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Bibliographic Details
Main Author: Jung, Young Chun
Format: Others
Published: Scholar Commons 2006
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Online Access:http://scholarcommons.usf.edu/etd/2577
http://scholarcommons.usf.edu/cgi/viewcontent.cgi?article=3576&context=etd