Differential coupling of RGS3s and RGS4 to GPCR-GIRK channel signaling complexes

'Regulators of G protein signaling' (RGS proteins) modulate the G proteincycle by enhancing the GTPase activity of Ga subunits. These changesaccelerate the kinetics of ion channel modulation by Gai/o-coupled receptors(GPCRs) such as the G protein-gated inward rectifier K+ (GIRK/Kir3) chann...

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Bibliographic Details
Main Author: Jaén, Cristina
Format: Others
Published: Scholar Commons 2006
Subjects:
Online Access:http://scholarcommons.usf.edu/etd/2571
http://scholarcommons.usf.edu/cgi/viewcontent.cgi?article=3570&context=etd