Src kinase inhibitors for the treatment of sarcomas: Cellular and molecular mechanisms of action

Sarcomas are rare mesenchymally-derived tumors with limited treatment options. Tyrosine kinases may serve as potential targets for sarcoma therapy because many are mutated or overexpressed in sarcomas and cell lines. One potential molecular target for sarcoma treatment is the Src tyrosine kinase. Th...

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Bibliographic Details
Main Author: Shor, Audrey Cathryn
Format: Others
Published: Scholar Commons 2007
Subjects:
Online Access:http://scholarcommons.usf.edu/etd/2364
http://scholarcommons.usf.edu/cgi/viewcontent.cgi?article=3363&context=etd