Mannich bases and other related compounds designed principally as candidate cytotoxic and anticancer agents

This study describes principally the synthesis of a number of Mannich bases of 1-aryl-1-ethanones, 4-aryl-3-buten-2-ones and their quaternary ammonium salts. These compounds were evaluated against P388 and L1210 leukemic cells, human T lymphocytes and a variety of human tumor cell lines. There were...

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Bibliographic Details
Main Author: Vashishtha, Sarvesh Chandra
Other Authors: Dimmock, Jonathan R.
Format: Others
Language:en
Published: University of Saskatchewan 1997
Online Access:http://library.usask.ca/theses/available/etd-10212004-000711