Synthesis of analogues of nordihydroguaiaretic acid and their oxidative metabolism
In order to investigate the structural features responsible for the cytotoxicity of the naturally occurring lignan nordihydroguaiaretic acid, the synthesis of four structural analogues of NDGA is proposed for the purpose of studying their oxidative metabolism. One analogue in particular (1), a mono-...
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Format: | Others |
Language: | en |
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University of Saskatchewan
2010
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Online Access: | http://library.usask.ca/theses/available/etd-05192010-134624/ |