Ligand-induced downregulation of the kinase-dead EphB6 receptor

Ligand-induced internalisation and subsequent downregulation of receptor tyrosine kinases (RTKs) serve to determine biological outputs of their signalling. Intrinsically kinase-deficient RTKs control a variety of biological responses, however, the mechanism of their downregulation is not well unders...

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Bibliographic Details
Other Authors: Freywald, Andrew
Language:English
Published: 2015
Subjects:
Online Access:http://hdl.handle.net/10388/ETD-2015-05-2057