Structure-Based Virtual Screening : New Methods and Applications in Infectious Diseases
A drug discovery project typically starts with a pharmacological hypothesis: that the modulation of a specific molecular biological mechanism would be beneficial in the treatment of the targeted disease. In a small-molecule project, the next step is to identify hits, i.e. molecules that can effect t...
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Format: | Doctoral Thesis |
Language: | English |
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Uppsala universitet, Avdelningen för organisk farmaceutisk kemi
2008
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Online Access: | http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-9302 http://nbn-resolving.de/urn:isbn:978-91-554-7297-9 |